Duke's staging of colorectal cancer



training.seer.cancer.gov



A: Tumour which does not extend beyond muscularis propria (layer of circular and longitudinal muscles) à 97% five year survival

B: Tumour extends across muscularis propria with no nodal involvement à 80% five year survival but dramatically worse prognosis if locally invasive

C1: Full thickness growth. Only a few nodes are involved near the primary growth  and the proximal nodes are free from metastasis à 60% 5 year survival

C2: Proximal nodes are involved à 30% five year survival

D: Distant metastasis à <5% 5 year survival